Chlorocol-H Eye Ointment contains chloramphenicol, a broad-spectrum antibacterial agent, and hydrocortisone, a corticosteroid. It is used to treat bacterial eye infections, reduce inflammation, and promote healing.

Key Features

How Chlorocol H eye Ointment Works

• Chloramphenicol prevents bacterial protein synthesis, destroying infecting bacteria.
• Hydrocortisone reduces inflammation, swelling, and redness by suppressing immune responses.

Uses

• Bacterial conjunctivitis
• Blepharitis
• Keratitis
• Other bacterial eye infections

Dosage

• Instil a small quantity (1-2 cm) in the affected eye 2-3 times daily.
• Complete the prescribed duration even if symptoms resolve.

Side Effects

• Transient stinging or burning
• Blurred vision
• Irritation of the eyes
• Rarely, allergic reactions

Pharmacokinetics

• Absorption: Minimal systemic absorption from ocular administration.
• Distribution: Primarily local within the eye.
• Metabolism: Chloramphenicol by liver; hydrocortisone by liver and tissues.
• Excretion: Chloramphenicol via urine; hydrocortisone via urine and feces.

Interactions

• Other eye drugs: Antivirals, antibiotics, and additional steroid drugs may interact.
• Systemic drugs: May interact with blood thinners (e.g., warfarin), diabetes drugs, and immunosuppressants.
• Increased risk of side effects with concurrent use of other corticosteroids or antibiotics.

Efficacy

• Effective for bacterial conjunctivitis, keratitis, blepharitis, and related infections.
• Symptom improvement often seen within a few days of use.
• Broad-spectrum antibiotic covers many bacteria causing eye infections.

Safety

• Minor side effects: stinging/burning, irritation, blurred vision.
• Rarely, serious effects: allergic reactions, aplastic anemia, bone marrow suppression.
• Prolonged hydrocortisone use may cause glaucoma or worsen fungal/viral infections.

Precautions

• Use cautiously if pregnant or breastfeeding.
• Do not use contact lenses during treatment.
• Monitor for infection or worsening symptoms.
• Let your doctor know if you have allergies or medical conditions.

Conclusion

Chlorocol-H Eye Ointment is effective for treating bacterial eye infections by reducing bacterial load and suppressing inflammation. Follow your doctor’s instructions, complete your course, and report any severe side effects promptly.

FAQ’s

1) What is Chlorocol-H eye ointment used for?

Treats bacterial eye infections, reduces inflammation and speeds healing.

2) Can I use Chlorocol-H when wearing contact lenses?

Remove contact lenses before application.

3) How soon does it work?

Symptoms usually improve within a few days.

4) Can I use it for viral infections?

No, use only for bacterial infections.

5) How does Chlorocol-H eye ointment work?

Chloramphenicol blocks bacterial protein synthesis; hydrocortisone reduces inflammation.

References

• https://www.ncbi.nlm.nih.gov/books/NBK555966/
• https://pmc.ncbi.nlm.nih.gov/articles/PMC2814277/