Cornigel 5 gm

Cornigel 5 gm Eye Ointment is a drug formulated to provide relief from dry eye syndrome and to protect and lubricate the ocular surface. Cornigel Eye Ointment contains three active pharmaceutical ingredients: White Soft Paraffin, Light Liquid Paraffin (Mineral Oil), and Lanolin, which work together to form a protective barrier on the eye surface, lock in moisture, and prevent moisture loss from the eyes.

Key Features

How does Cornigel 5 gm eye ointment work?

• Forming a protective barrier: White Soft Paraffin and Light Liquid Paraffin create a smooth, protective film over the eye surface that shields the eyes from external irritants and environmental factors.
• Locking in moisture: The combination of emollients works to trap moisture on the eye surface, preventing evaporation and maintaining adequate hydration of the cornea and conjunctiva.
• Soothing and lubricating: Lanolin acts as an additional emollient that softens, soothes, and lubricates dry, irritated eyes, providing relief from discomfort.
• Preventing moisture loss: The combined effects of these three ingredients create a long-lasting protective layer that reduces tear evaporation and keeps the eyes moist, helping to alleviate symptoms associated with dry eye syndrome such as burning, itching, redness, and the sensation of something being in the eye.

Dosage

• Apply a small amount (about 0.6 cm or one-fourth inch) of ointment inside the lower eyelid of the affected eye, 2-3 times a day or as directed by your doctor.
• For prolonged overnight relief, apply the ointment before bedtime.
• It is recommended to consult a doctor or medical professional prior to using eye ointment for better results.

Uses

• Dry eye syndrome: A chronic condition where the eyes don’t produce enough tears or produce poor-quality tears, leading to eye discomfort, burning, itching, and redness.
• Eye irritation: Relief from eye irritation caused by environmental factors such as wind, sun, heating/air conditioning, prolonged computer use, or reading.
• Eye protection: Protects the eye surface from injury and infection while keeping it moist.
• Post-surgical care: Used after eye surgeries to maintain moisture and protect the healing eye surface.

Side Effects

• Temporary blurred vision immediately after application
• Mild stinging or burning sensation
• Eye discomfort or irritation
• Watery eyes
• Slight redness of the eyes
• Sticky eyelids upon waking (if applied before bedtime)

Interactions

• Cornigel 5 gm Eye Ointment has minimal systemic absorption and is not known to have significant interactions with oral medications.
• If you are using multiple eye medications, maintain a time gap of at least 5 minutes between different eye drops or ointments.
• Always apply eye drops before eye ointment to allow proper absorption of the drops.
• Eye ointment should always be applied after eye drops, never before.
• Remove contact lenses before applying Cornigel Eye Ointment and wait at least 15 minutes before reinserting them.

Pharmacokinetics

Pharmacokinetics of Cornigel Eye Ointment involves the topical application of the active components to the eye surface, where they form a protective barrier and provide lubrication. The medication acts locally on the ocular surface with minimal to no systemic absorption. The ointment remains on the eye surface for an extended period, providing prolonged relief from dry eye symptoms. The complete pharmacokinetic properties of this drug are not extensively documented due to its local action and minimal systemic exposure.

Precautions

• Allergies: Do not use Cornigel Eye Ointment if you are allergic to White Soft Paraffin, Light Liquid Paraffin, Lanolin, or any other ingredients in the formulation.
• Contact lenses: Remove contact lenses before applying the ointment and wait at least 15 minutes before putting them back in. However, it is generally advised not to wear contact lenses when experiencing dry eye symptoms.
• Pregnancy and breastfeeding: Cornigel Eye Ointment is generally considered safe during pregnancy and breastfeeding as it has minimal systemic absorption. However, consult your doctor before using if you’re pregnant or breastfeeding.
• Children: Use with caution in children and only under medical supervision. The product is generally safe for pediatric use when appropriately dosed.
• Elderly patients: Safe for use in elderly patients. No specific dose adjustments are required.
• Contamination: Do not touch the tip of the tube to any surface including your eye, fingers, or eyelashes to avoid contamination.
• Vision impairment: May cause temporary blurred vision after application. Avoid driving or operating machinery until your vision clears.
• Product discoloration: Do not use the ointment if it changes color or appearance.
• Use within 4 weeks: Once opened, the medication should be used within 4 weeks to ensure sterility and effectiveness.
• Eye infections: If you have or suspect an eye infection, consult your doctor before using this product.
• Persistent symptoms: If symptoms persist or worsen after 72 hours of use, discontinue and consult your doctor immediately.

Conclusion

Cornigel 5 gm Eye Ointment is an effective drug for the management of dry eye syndrome and eye irritation. By forming a protective barrier and locking in moisture on the eye surface, this ointment provides long-lasting relief from symptoms such as burning, itching, redness, and the feeling of something in the eye. It is particularly useful for nighttime application due to its thick consistency and prolonged action. However, for avoiding side effects and ensuring optimal results, it’s essential to adhere to the dosing instructions and precautions. Consult your physician or an eye specialist for specific recommendations and information on using Cornigel Eye Ointment.

References

• https://www.researchgate.net/publication/264389740_Enhanced_corneal_permeation_and_antimycotic_activity_of_itraconazole_against_Candida_albicans_via_a_novel_nanosystem_vesicle
• https://doi.org/10.1371/journal.pone.0248857

FAQ’s