Digihaler SF 250 Inhaler

Digihaler SF 250 is a smart pressurised metered‑dose inhaler (MDI) delivering Fluticasone propionate 250 mcg and Salmeterol 25 mcg per actuation. It uses the CFC‑free propellant HFA‑134a and comes in a canister fitted with a plastic actuator and mouthpiece.

Key Features

 How does Digihaler SF 250 Inhaler work?

• Airway muscle relaxation: Salmeterol, being a long-acting beta2-adrenergic agonist (LABA), relaxes the airway muscles, widens the airways, and makes breathing easier.
• Reducing inflammation: Fluticasone Propionate, a corticosteroid, reduces airway inflammation, inhibiting signs such as wheezing, cough, and breathlessness.

Usage

• Suppress asthma symptoms: Prevent and suppress asthma symptoms, such as wheezing, cough, and breathlessness.
• Control COPD: Control symptoms of chronic obstructive pulmonary disease, such as breathlessness and wheezing.

Dosage

The dose usually prescribed is 2 puffs twice a day, but it can vary based on the severity of the illness and patient needs. It’s important to utilize the dosage as directed by your doctor.

Side Effects

• Headache
• Irritation of the throat
• Hoarseness or voice alteration
• Oral candidiasis (mouth fungal infection)Add product gallery images
• Cough
• Musculoskeletal pain
• Tachycardia

Interactions

• Beta-blockers: Can decrease the efficacy of Salmeterol.
• Ketoconazole and other antifungals: Can enhance the levels of Fluticasone Propionate.
• Ritonavir and other HIV protease inhibitors: Can enhance the levels of Fluticasone Propionate.

Pharmacokinetics

• Absorption: Salmeterol and Fluticasone Propionate get absorbed into the blood after inhalation.
• Distribution: Both drugs are distributed to different areas of the body, and Salmeterol’s volume of distribution is greater.
• Metabolism: Salmeterol is metabolized by CYP3A4 enzyme of the liver, whereas Fluticasone Propionate is metabolized by CYP3A4 enzyme of the liver and by other enzymes.
• Elimination: Both drugs are eliminated from the body via feces and urine.

Safety and Efficacy

• Safety precaution: Should be used cautiously in pregnant women, lactating mothers, and patients with hepatic or renal impairment.
• Common side effects include headache, throat irritation, hoarseness, nausea, and vomiting.
• Serious side effects include allergic reaction, adrenal suppression, worsening of breathing problems, and quickened pulse

Efficacy

• Effective in the management of asthma and COPD symptoms: decreases the frequency and severity of asthma attacks and COPD exacerbations.
• Improves lung function: increases airflow and makes breathing easier
• Long-term maintenance therapy: Symptom control and prevention of future attacks Dosage and use should be according to prescription for maximum efficacy and least side effects.
• Consult a physician before administration for personal advice and guidance

Precautions

• Rinse your mouth with water after each use to avoid oral candidiasis.
• If you’re diabetic, keep a close eye on your blood sugar levels because Digihaler SF 250 Based Inhaler can impact blood sugar levels.
• Regarding any previous medical conditions like kidney or liver impairment and other medications taken.

Conclusion

Digihaler SF 250 Inhaler is a good medication for treating asthma and COPD symptoms. By learning how it functions, using the correct dosage, and being knowledgeable about side effects and interactions, you can safely and effectively use this drug.

References

https://www.ncbi.nlm.nih.gov/books/NBK557453/

https://www.ncbi.nlm.nih.gov/books/NBK542161/

FAQ’s