Dorzox Eye Drops 2% is an ophthalmic solution containing Dorzolamide Hydrochloride, a carbonic anhydrase inhibitor used to reduce intraocular pressure (IOP) in patients with glaucoma and ocular hypertension. The active pharmaceutical ingredient, Dorzolamide, decreases fluid production in the eye.
Key Features
| About Dorzox 2% 5 ml Eye Drop | |
|---|---|
| Drug Class | Ophthalmic agents |
| Subclass | Topical Carbonic Anhydrase Inhibitors |
| Product Details | |
|---|---|
| Composition | Active ingredients: Dorzolamide (2% w/v) Inactive ingredients:
|
| Packaging Type | Dropper Bottle |
| Pack Size | 5 ml |
| Dosage | 1 drop in the affected eye, twice a day or as directed by your doctor |
| Therapeutic Class | Ophthalmic |
| Action Class | Intraocular pressure-reducing agent |
| Chemical class | Sulfonamide Derivative, Thiophenes Derivative |
| Manufacturer | Cipla Ltd, Intas |
| Shelf Life | 2-3 years from the date of manufacturing |
| Usages | Treatment of Glaucoma, Ocular hypertension |
| Country of Origin | India |
| Storage | Store at room temperature (25°-30°C) away from moisture and direct sunlight. |
How does Dorzox 5 ml eye drop work?
- Reducing the production of fluid in the eye: Dorzolamide, a carbonic anhydrase inhibitor, decreases the production of fluid in the eye.
- Enhancing drainage of fluid from the eye: Dorzolamide helps to increase the drainage of fluid from the eye.
- Decreasing intraocular pressure: The combined effects reduce the pressure within the eye, helping to prevent vision loss and alleviate symptoms associated with glaucoma and ocular hypertension.
Dosage
- 1 drop in the affected eye, twice a day or as directed by your doctor.
- Consult a doctor or medical professional prior to using eye drops for better results.
Uses
- Open-angle glaucoma: A chronic, progressive condition that can cause vision loss if untreated.
- Ocular hypertension: Elevated pressure within the eyes that can lead to optic nerve damage.
Side Effects
- Stinging or burning sensation in the eye
- Blurry vision
- Redness and itching of the eyes
- Bitter taste
- Headache
- Dizziness
- Dryness of the eyes
Interactions
- Dorzox 5 ml can interact with Aspirin, increasing risk of side effects like eye irritation and blurry vision.
- Eye drop may interact with Clonidine, potentially lowering blood pressure.
- Interaction with Theophylline may decrease Dorzox effectiveness.
- Formoterol may reduce benefits of both drugs when used with eye drops.
- Interaction with Atazanavir may increase risk of abnormal heart rhythms.
Pharmacokinetics
Pharmacokinetics of Dorzox Eye Drops involve absorption of active components where they exert their action. Complete pharmacokinetic properties remain partly unknown.
Precautions
- Do not use if allergic to Dorzolamide.
- Use caution if suffering from asthma or COPD.
- Use with caution if heart failure, slow or irregular heartbeat, or cardiogenic shock present.
- Exercise caution in kidney or liver disease.
- Consult doctor if pregnant or breastfeeding.
- Remove contact lenses before administration and wait at least 15 minutes before reinsertion.
Conclusion
Dorzox 5 ml Eye Drops effectively treat open-angle glaucoma and ocular hypertension by reducing fluid production and increasing outflow, lowering intraocular pressure and preventing vision loss. To avoid side effects and interactions, follow dosage and precautions, and seek advice from your doctor or eye specialist.
References
https://pubchem.ncbi.nlm.nih.gov/compound/Dorzolamide
https://pubmed.ncbi.nlm.nih.gov/9143858/
Anastasia Petrova –
This one is straightforward and works on eye pressure control. It does sting a little, but that fades fast. Better than some other brands I tried before