Poxet 90 mg

Poxet 90 mg is a medication used for various erectile issues like Premature ejaculation and also in low libido. Poxet 90 mg may contain dapoxetine as an active ingredient it may work by enhancing the level of serotonin in the brain, that permits ejaculation to be delayed. It is specifically formulated for rapid onset and fast duration of action. Dapoxetine is also known as Selective serotonin reuptake inhibitor, it helps in delaying ejaculation and improve control over premature ejaculation.

How does Poxet 90 mg work?

Poxet inhibits neuronal reuptake of serotonin and then potentiation of serotonin activity. Poxet, by elevating levels of serotonin in the brain, retards ejaculation and enhances ejaculatory latency control.

• Poxet is a type of drug known as selective serotonin reuptake inhibitors (SSRIs).
• It raises the level of serotonin in the nervous system, there by delaying ejaculation and enhancing ejaculation control.

 Usage

• Poxet (dapoxetine medication) can be used to treat premature ejaculation.
• Other sexual issues can also be treated.

Dosage

• The starting dose of Poxet is 30 mg, it can be extended up to 60 mg and 90 mg according to individual requirement.
• It can be taken 1-3 hours before sexual activity.
• It is recommended to consult a healthcare provider or doctor to avoid any unwanted interactions and for the better results.

Strengths of Poxet

• Poxet 30 mg
• Poxet 60 mg

Side effects

• Nausea
• Dizziness
• Headache
• Diarrhea
• Insomnia
• Anxiety
• Fatigue
• Serotonin syndrome

 Interactions

• Poxet can be taken with other serotonergic drugs, including selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), or monoamine oxidase inhibitors (MAOIs), can enhance the risk of serotonin syndrome and leads to severe side effect.
• Co-administration of Poxet with PDE5 inhibitors can enhance the risk of orthostatic hypotension.
• Poxet is metabolized by liver enzymes CYP2D6 and CYP3A4. Concomitant administration of drugs that inhibit these enzymes can lead to increased body concentrations of Poxet and potentially enhance the risk of side effects.
• Poxet can interact with other drugs, including thioridazine, and make it more likely to have side effects.

Pharmacokinetics

• It is absorbed rapidly, it reaches at peak in just 1-2 hours.
• The bioavailability is about 42% due to its first pass hepatic metabolism.
• If it is administered with food may slightly delay the absorption.
• It is extensively distributed in the tissue 1623 litres. It is highly bounded to plasma proteins.
• It is primarily metabolized, Hepatic metabolism i.e., CYP3A4, CYP2D6.
• It is excreted through urine approx. and feces.
• The half-life is approx. 1.5 hours.

Precautions

• Consult a medical professional or any healthcare provider prior taking any such medications if you are with any prior medical history of cardiac condition, renal impairment, hepatic impairment.
• Avoid grape fruits, alcohol as it may leads to serious interactions.
• Poxet may shows contraindications with monoamine oxidase inhibitors (MAOIs), thioridazine, or other serotonergic drugs so it should be avoided.
• Poxet should not be used in women’s during pregnancy and lactation is unknown.

Conclusion

Poxet (dapoxetine) is a drug that provides a best solution for premature ejaculation. Just by increasing levels of serotonin level in the brain, Poxet postpones ejaculation and enhances ejaculatory latency control. Though it can cause side effects and interact with other drugs, Poxet was found to be effective and safe in clinical trials. It is required to consult a healthcare provider prior using any such medications just to avoid any interactions and also for best results.

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