TADARISE

TADARISE 2.5MG

Ideal for: Daily use therapy and mild erectile dysfunction

• Lowest strength option for continuous daily treatment
• Perfect for men who engage in sexual activity more than twice weekly
• Has a minimal side effects profile
• Can be taken with or without food

TADARISE 5MG

Ideal for: Regular daily use and moderate ED symptoms

• Standard daily dose for most patients
• Maintains consistent medication levels in the body
• Suitable for men with diabetes or cardiovascular conditions
• Excellent safety profile for long-term use

TADARISE 20MG

Ideal for: On-demand treatment for moderate to severe ED

• Most commonly prescribed strength worldwide
• Effective for 24-36 hours after consumption
• Take 30-60 minutes before planned sexual activity
• Suitable for occasional use (not more than once daily)

TADACIP 20MG

Ideal for: Cost-effective alternative for moderate ED

• Same active ingredient and effectiveness as brand medications
• Proven bioequivalence to original formulations
• Manufactured under strict quality standards
• Excellent value for money option

TADARISE 40MG

Ideal for: Severe erectile dysfunction cases

• Higher strength for men who don’t respond to lower doses
• Requires careful medical supervision
• Not recommended for first-time users
• Should be used only under specialist guidance

TADARISE 60MG

Ideal for: Most severe cases of ED with medical supervision

• Maximum strength option available
• Reserved for patients with severe ED who haven’t responded to lower doses
• Requires comprehensive medical evaluation before prescription
• Enhanced monitoring for side effects necessary

SUPER TADARISE

Ideal for: Dual action – ED plus premature ejaculation

• Contains: Tadalafil 20mg + Dapoxetine 60mg
• Addresses both erectile dysfunction and premature ejaculation
• Dapoxetine component delays ejaculation for improved sexual performance
• Comprehensive solution for complete sexual wellness

EXTRA SUPER TADARISE

Ideal for: Maximum dual-action treatment

• Contains: Tadalafil 40mg + Dapoxetine 60mg
• Highest strength combination for severe ED with PE
• Reserved for patients requiring maximum therapeutic effect
• Requires specialist consultation and monitoring

Uses and Medical Applications

Primary Uses

• Treatment of Erectile Dysfunction (ED): All strengths effectively treat varying degrees of erectile dysfunction by improving blood flow to penile tissues
• Pulmonary Arterial Hypertension (PAH): Lower strengths (2.5mg, 5mg) used daily for managing PAH symptoms
• Benign Prostatic Hyperplasia (BPH): Daily low-dose therapy helps reduce urinary symptoms associated with enlarged prostate

Specialized Applications

• Super and Extra Super Tadarise: Dual treatment for ED combined with premature ejaculation
• Daily Therapy: Low doses (2.5mg, 5mg) for continuous treatment and spontaneous sexual activity
• On-Demand Treatment: Higher doses (20mg, 40mg, 60mg) for planned sexual encounters

Benefits and Mechanism of Action

How Tadarise Works

Tadarise belongs to the phosphodiesterase type 5 (PDE5) inhibitor class. During sexual arousal, nitric oxide is released in the penile tissues, activating the enzyme guanylate cyclase. This increases levels of cyclic guanosine monophosphate (cGMP), causing smooth muscle relaxation and increased blood flow to the penis.

PDE5 enzyme breaks down cGMP, ending the erection. Tadarise inhibits PDE5, maintaining higher cGMP levels and prolonging erection duration. This mechanism ensures erections occur only with sexual stimulation, making it a natural and effective treatment.

Key Benefits

• Long Duration: Effects last 24-36 hours, providing flexibility for sexual activity
• Quick Onset: Begins working within 30-60 minutes
• Food Independence: Can be taken with or without meals (except high-fat meals which may delay absorption)
• Proven Efficacy: Over 80% success rate in clinical studies
• Improved Confidence: Restores sexual confidence and relationship satisfaction

Dosage Guidelines and Administration

Starting Recommendations

• First-time users: Begin with 10-20mg as needed
• Daily therapy users: Start with 2.5mg daily, may increase to 5mg
• Severe cases: May require 40mg or 60mg under medical supervision
• Combination therapy: Super or Extra Super Tadarise for dual symptoms

Administration Instructions

1. Timing: Take 30-60 minutes before planned sexual activity
2. Frequency: Not more than once in 24 hours for on-demand use
3. Food: Can be taken with light meals; avoid high-fat foods
4. Alcohol: Limit alcohol consumption as it may reduce effectiveness
5. Storage: Store in cool, dry place away from direct sunlight

Side Effects and Safety Profile

Common Side Effects (Generally Mild and Temporary)

• Headache (most common, affects 10-15% of users)
• Facial flushing and warmth
• Nasal congestion
• Back pain and muscle aches
• Indigestion and stomach upset
• Dizziness or lightheadedness
• Blurred vision or color vision changes

Serious Side Effects (Seek Immediate Medical Attention)

• Sudden vision loss or severe vision changes
• Sudden hearing loss or ringing in ears
• Chest pain or irregular heartbeat
• Severe dizziness or fainting
• Erection lasting more than 4 hours (priapism)
• Severe allergic reactions (rash, difficulty breathing, swelling)

Safety Considerations by Strength

• Lower doses (2.5-5mg): Minimal side effects, suitable for daily use
• Medium doses (20mg): Well-tolerated by most patients
• Higher doses (40-60mg): Increased risk of side effects, requires monitoring
• Combination products: Additional side effects from dapoxetine component

Contraindications and Precautions

Absolute Contraindications

• Nitrate medications: Never combine with nitroglycerin, isosorbide, or other nitrates
• Recent cardiovascular events: Heart attack within 90 days, stroke within 6 months
• Severe heart conditions: Unstable angina, severe heart failure
• Severe liver disease: Child-Pugh Class C liver impairment
• Hypotension: Blood pressure below 90/50 mmHg
• Retinitis pigmentosa: Hereditary eye condition
• Allergy to tadalafil: Known hypersensitivity to the active ingredient

Relative Contraindications (Use with Caution)

• Mild to moderate liver impairment
• Kidney disease requiring dialysis
• History of priapism or penile deformities
• Active peptic ulcer disease
• Bleeding disorders or active bleeding
• Concurrent use with alpha-blockers

Drug Interactions and Warnings

Major Drug Interactions

• Nitrates: Life-threatening blood pressure drop
• Alpha-blockers: Additive hypotensive effects
• Antifungals: Ketoconazole, itraconazole increase tadalafil levels
• Antibiotics: Erythromycin, clarithromycin may increase side effects
• HIV medications: Ritonavir significantly increases tadalafil concentration
• Blood pressure medications: May enhance hypotensive effects

Lifestyle Considerations

• Alcohol: Moderate consumption acceptable, excessive drinking reduces effectiveness
• Grapefruit: May increase tadalafil levels, consume in moderation
• Driving: Avoid if experiencing dizziness or visual disturbances
• Exercise: Safe with normal physical activity, avoid strenuous exercise immediately after taking

Storage and Handling Guidelines

Proper Storage Conditions

• Temperature: Store at room temperature (15-30°C/59-86°F)
• Humidity: Keep in dry place, protect from moisture
• Light: Store in original packaging, protect from direct sunlight
• Accessibility: Keep out of reach of children and pets
• Expiration: Check expiry dates regularly, do not use expired medication

Disposal Instructions

• Do not flush down toilet or sink
• Return unused medications to pharmacy take-back programs
• Remove personal information from packaging before disposal
• Follow local guidelines for pharmaceutical waste disposal

Quality Assurance and Manufacturing

All Tadarise products are manufactured under strict Good Manufacturing Practice (GMP) guidelines, ensuring consistent quality, purity, and potency. Each batch undergoes rigorous testing for active ingredient content, dissolution rates, and stability. The manufacturing facilities are regularly inspected by regulatory authorities to maintain the highest quality standards.

Conclusion

The Tadarise product range offers comprehensive solutions for erectile dysfunction treatment, from mild daily therapy options to maximum-strength formulations for severe cases. With proper medical guidance and adherence to dosage instructions, Tadarise products provide safe, effective treatment that can significantly improve quality of life and sexual wellness. Always consult with a healthcare provider to determine the most appropriate strength and formulation for your individual needs.