Hepaglide 0.25 mg Injection

Hepaglide 0.25 mg Injection is indicated for cardiovascular risk reduction and weight management in adults with obesity or overweight. It works best when combined with a reduced calorie diet and regular physical activity. It is generally injected under the skin in the abdomen, thigh or upper arm. 

Key Features

How does Hepaglide 0.25 mg work?

Hepaglide 0.25 works by mimicking the action Glucagon-like peptide (GLP), a natural hormone in the body that helps control appetite. It reduces hunger and food cravings. It also helps the body to regulate sugar levels. 

Directions for use

• Hepaglide injection is administered once weekly at the same day subcutaneously. 
• Do not self administer without proper training and medical guidance. 
• It is better if given by a trained professional. 

Dosage

Use as and when directed by the healthcare provider. 

Uses

Hepaglide 0.25 mg is used for:

• Cardiovascular risk reduction
• Type 2 Diabetes
• Chronic weight management in adults with obesity and overweight

Side effects 

• Headache
• Constipation
• Severe dehydration
• Hypoglycemia 
• Redness, pain at the site of injection
• Fatigue
• Digestive discomfort
• Allergic reactions

Interactions

• Semaglutide alters the absorption of medications including thyroid medications, oral contraceptives, diuretics, blood pressure medications and pain relievers. 
• Semaglutide should be avoided with other GLP-1 agonists like Liraglutide, Tirzepatide.
• Herbal supplements like gymnema, bitter melon or fenugreek if taken with Semaglutide can cause blood sugar to drop too drastically. 
• Coadministration of Hepaglide along with Gatifloxacin may sometimes affect blood glucose levels. 
• Concomitant use of Hepaglide with Bexarotene will increase the risk of pancreatitis. 
• Avoid sulfonylureas like glimepiride, glipizide and insulin as it can increase the risk of hypoglycemia. 

Precautions & Warnings

• To prevent skin irritation or lumps, change the site of administration every week.
• Drink plenty of water to counteract dehydration.
• Do not use the injection if you or a close family member had a history of thyroid cancer like medullary thyroid carcinoma or Multiple endocrine Neoplasia Syndrome type 2.
• The injection is not recommended for children below the age of 18 years. 
• Do not use the injection if you are pregnant, planning pregnancy or breastfeeding. 
• Do not share the injection with other users. 
• Patients with renal impairment should use the injection with caution especially if severe nausea, vomiting or dehydration occurs. 
• Some people might experience dizziness during dose escalation. Do not drive during such times. 
• Contact your physician immediately if you experience any severe or persistent side effects.

Conclusion

Hepaglide 0.25 mg injection is a medication that is used to support weight management along with Type-2 diabetes. It should be used once a week, usually on the same day. The medicine works best and safely when paired with a healthy reduced calorie diet and regular exercising. It should be used under medical supervision. 

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