Estradiol is an FDA-approved drug used in treating:

• Hormonal Replacement therapy (HRT)
• Menopause symptoms
• PCOS and PCOD
• Osteoporosis
• Hypoestrogenism

No need to worry much, we’re with the best solution Estrabet 2 Tablet, Evatone 2, Esurance Tablet, Progynova 1 mg, Valest 2 Tablet, Estrahenz Tablet, Estrabet 1 Tablet, Valest 1 Tablet, Oestrogel Gel 80 gm, and Estradiol 2 mg tablet.

How does Estradiol work?

• Estradiol may circulates in blood and may enters target cells followed by diffusion in cell membrane.
• It may bind to estrogen receptors i.e., ER α and ER β inside the cell in the nucleus.
• This drug-receptor complex may get attached to DNA at estrogen response elements.
• The genes on or off occurs due to binding and this help the cell to produce specific proteins.

Safety and Efficacy

• According the safety concern it may shows some side effects i.e., irregular vaginal bleeding, breast tenderness, vaginal yeast infection, upper respiratory infection, nausea, headache, dizziness, fluid and retention this side effects may vary from individual to individual but need to prior consult your health care professional to avoid unwanted interactions.
• Efficacy, as it is FDA approved for moderate to severe hot flashes and vulvar/ vaginal atrophy, osteoporosis prevention, hypoestrogenism, and rarely used in certain breast or prostate cancer.

Precautions

• Need to follow regular check-ups, as doctor should check progress in every 3-6 months.
• The conditions like Asthma, Epilepsy, Migraine, Diabetes, Lupus and Endometriosis need proper monitoring, to avoid interactions and side effects.
• Topical gel transfer, avoid skin contact with others for about 1+ hour.
• Avoid such medications during pregnancy and breast feeding.