Livarise Pen Injector Pen

Livarise injector pen is a glucagon-like peptide-1 (GLP-1) receptor agonist used for Type 2 diabetes and weight management and obesity. It contains Semaglutide as a base and comes as a subcutaneous injection pen once weekly. This prefilled pen is designed for simple and accurate dosing.  

Key Features

How does the Livarise Injector pen work?

Livarise injector pen consists of Semaglutide. Semaglutide is a GLP-1 receptor agonist. It acts similarly to the body’s natural GLP-1 (glucagon-like peptide-1) hormone, which is released after meals to regulate blood sugar levels and appetite. It also slows down digestion so the food stays in the body for a little longer. It decreases appetite and food intake. 

Directions for use

• Wash your hands thoroughly. Select the site of injection and rotate it each week. 
• Wipe the skin with an alcohol swab and let it dry completely. 
• Remove the protective cap from the pen and screw a sterile pen needle into the pen. 
• Prime the pen and dial your prescribed dose as instructed by the healthcare provider. 
• Inject the needle straight under the skin at a 90 degree angle. Push the injection button in the skin. 
• Carefully remove the needle and replace the pen cap. 

Dosage

Use as and when prescribed by the healthcare provider. 

Uses

Livarise injector pen is used for:

• Chronic weight management
• Cardiovascular risk reduction
• Type 2 Diabetes

Side effects 

• Nausea
• Vomiting
• Diarrhea
• Constipation
• Fatigue
• Reduced appetite
• Headache and dizziness
• Digestive discomfort
• Redness, pain and swelling at the site of injection
• Severe, persistent stomach pain
• Severe dehydration
• Hypoglycemia
• Serious allergic reactions
• Diabetic retinopathy (serious)

Interactions 

• Antidiabetic medications

Semaglutide should be avoided with other GLP-1 agonists like Liraglutide, Tirzepatide. Avoid sulfonylureas like glimepiride, glipizide and insulin as it can increase the risk of hypoglycemia. 

• Oral medications

Semaglutide delays stomach emptying. This alters the absorption of medications including thyroid medications, oral contraceptives, diuretics, blood pressure medications and pain relievers. 

• Herbal supplements

Herbal supplements like gymnema, bitter melon or fenugreek if taken with Semaglutide can cause blood sugar to drop too drastically. 

• Antibiotics and antimalarial drugs

Certain antibiotics and antimalarial drugs like clarithromycin, hydroxychloroquine can compound stomach side effects or alter blood sugar. 

• Loop Diuretics

Loop diuretics like furosemide, torsemide when taken with semaglutide may increase the risk of hypoglycemia.

• Insulin and sulfonylureas

Concomitant use of  insulin and sulfonylureas along with semaglutide can increase the risk of hypoglycaemia (low blood sugar levels).

Precautions & Warnings

• Store the Livarise injector pen in a temperature between 35.6-46.4℉. Do not freeze the pen. 
• Rotate injection sites weekly. 
• Do not use the injection if it appears cloudy, discoloured or contains clumps. 
• Do not inject into skin that is bruised, scarred or within 2 cm of your belly button, hips or ribs. 
• Use a fresh, sterile needle for every single injection. 
• It is not safe to be used during pregnancy or while breastfeeding. 
• Discard all used needles and pens in a safe disposal container. 
• Do not use the product if you are allergic to Semaglutide or any other ingredient of the product.
• Semaglutide has a warning for the risk of thyroid C-cell tumours. 

Conclusion

Livarise injector pen is a medication that is used to support weight management along with Type-2 diabetes. It should be used once a week, usually on the same day. The medicine works best and safely when paired with a healthy reduced calorie diet and regular exercising.  Use the pen exactly as prescribed by the healthcare provider. 

FAQ’s